Lipogenesis in rabbit adipose tissue

Lipogenesis in ovine adipose tissue in tissue culture.

Lipogenesis in brown adipose tissue and its regulation.

acids and ketone bodies in the circulation, and there is a need to conserve glucose because of the relatively low carbohydrate content of the milk (for review see Williamson, 1985). During this period of development, brown adipose tissue has a vital role in thermogenesis, and the level of GDP-binding to brown-fat mitochondria is considerably increased (Sundin & Cannon, 1980). The weight of inte...

Effect of propionate on lipogenesis in adipose tissue.

The metabolism of propionate in adipose tissue and its effect on lipogenesis was investigated. Fasting induced changes in propionate metabolism of adipose tissue, drastically reducing higher fatty acid synthesis and increasing glyceride-glyerol formation from low concentrations of propionate (0.25 mM). Propionate also promoted lipogenesis from acetate-1-(14)C in tissues of fasted rats, while it...

Hepatic oleate regulates adipose tissue lipogenesis and fatty acid oxidation.

Hepatic steatosis is associated with detrimental metabolic phenotypes including enhanced risk for diabetes. Stearoyl-CoA desaturases (SCDs) catalyze the synthesis of MUFAs. In mice, genetic ablation of SCDs reduces hepatic de novo lipogenesis (DNL) and protects against diet-induced hepatic steatosis and adiposity. To understand the mechanism by which hepatic MUFA production influences adipose t...

A tissue-specific increase in lipogenesis in rat brown adipose tissue in hypothyroidism.

1. Rats were made hypothyroid by feeding them with propylthiouracil together with a low-iodine diet for 4 weeks. 2. [U-14C]Glucose conversion into fatty acids was substantially enhanced in brown adipocytes isolated from hypothyroid rats. Incorporation of 3H2O into fatty acids in vivo was enhanced in hypothyroidism in interscapular brown fat, but not in epididymal white fat or in liver. Hypothyr...